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banner image for SPE-03 performing automated protein purification with HiStrap, gravity and SPE columns

Automated High Throughput Purification of

Proteins and other Biomolecules

  • Antibody Purification
  • Antigen and Enzyme Extraction
  • Metabolite Profiling
  • Oligonucleotide Extraction
Up to 20x faster than manual protein purification
SPE-03 system setup for automated protein purification, antibody purification, antibody extraction

SPE-03 8-Channel System

Automated purification of 8 samples in parallel, up to 1L samples.
using as many as 9 buffer solutions.

Compatible with 1mL to 70mL columns
eg. GE HiStrapTM, gravity-flow columns and standard SPE cartridges.

Positive-pressure liquid delivery ensures consistent flow rate and fixed process time for each protein purification batch. Supervision is no longer required for gravity-flow columns, all samples start and finish simultaneously. Controlled flow also allows for increased column packing capacity for even higher sample throughput.

Up to 2 fractions per sample enabling targeted automated extraction of biomolecules and method development. More fractions can be collected by programming pause steps and switching out fraction tubes.

Automated column regeneration possible depending on application.

Customizations available upon request.

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Operates under temperatures low as

4°C

For proteins such as enzymes and antigens that require low temperature preservation

SPE-03 performing automated protein purification of antigens at low temperature

Highly Inert and Corrosion Resistant

Compatible with biological samples, acids, bases and salts

SPE-03 performing automated protein purification of antibodies using inert material

Easily Programmable Touch Interface

Saves up to 100 methods for automated protein purification, system cleaning and column regeneration

SPE-03 user interface for automated protein purification

Automated Protein Purification Steps:

Condition Column Load Sample Wash Column Elute Clean System Regenerate Column
Choose from up to 9 buffers to condition columns Deliver up to 1L of samples such as cell lysate or other biological fluids through columns Choose from up to 9 buffers to remove impurities Elute columns using selected buffer(s). Can collect up to 2 separate fractions automatically. Choose from up to 9 buffers to clean sample and column lines Wash and regenerate columns with buffer(s) and preserving agent(s)
Condition Column Choose from up to 9 buffers to condition columns
Load Sample Deliver up to 1L of samples such as cell lysate or other biological fluids through columns
Wash Column Choose from up to 9 buffers to remove impurities
Elute Elute columns using selected buffer(s). Can collect up to 2 separate fractions automatically.
Clean System Choose from up to 9 buffers to clean sample and column lines
Regenerate Column Wash and regenerate columns with buffer(s) and preserving agent(s)